In my opinion you just need to find a hardware/software
combination that works best for you. I started using Performer
when it was a MIDI only app and found it to be a very good
sequencing enviorment with very flexible swing and quantize
options. That has alot to do with "feel".
I also use Reason for creating tracks
and have started using my Oberheim DMX for drums again.
Many of my Hip Hop clients use and love various MPC models
along with Tritans, Motifs etc...
There is something to be said for a hardware box that just
"does it's thing" That said those devices also have their limits.
Choose what makes you most comfortable for the type
of music you make.

BTW this is Soy Sos of Tuff Sound Recording.
tuffsoundrecording.com
I am new to this group and am awaiting
my first Doepfer rack. It will be used mainly
for signal processing in combination with
my APR 2600 and studio/performance setups.
This is what I'm getting:

A-100G6 with PSU2
A-121 multimode filter
A-101-1 vactrol multi mode filter
A-125 phase shifter
A-188 1-B (1024 stage) analog delay
A-136 distortion / waveshaper
A-119 external input / envelope follower
A-180 multiples
A-138b mixer